Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant fragment within Human PPM1G aa 300-450. The exact sequence is proprietary.Database link: O15355
Applications
Application Notes
Flow Cyt: 1/250; WB: 1/10000 - 1/50000.
Target
Alternative Names
PPM1G; protein phosphatase, Mg2+/Mn2+ dependent, 1G; protein phosphatase 1G (formerly 2C), magnesium dependent, gamma isoform; protein phosphatase 1G; PP2C; gamma; PP2CG; PP2Cgamma; protein phosphatase 2C; gamma isoform; PP2C-gamma; PP2C, gamma; protein p
Product Background
Antigen Description
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
Pathway
mRNA processing, organism-specific biosystem.
Citations
Publication ()
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COA
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