Anti-PORCN polyclonal antibody (DPABH-10015)

Rabbit anti-Human PORCN (full length) polyclonal antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Full length protein corresponding to Human PORCN aa 1-450. (NP_073736.2).Sequence: MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSY LKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLS VTILIYLLMGEMHMVDTVTWHKMRGAQMIVAMKAVSLGFDLDRGEVGTVP SPVEFMGYLYFVGTIVFGP
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PORCN; porcupine homolog (Drosophila); PPN; DHOF; FODH; MG61
Entrez Gene ID
UniProt ID

Product Background


Pathway
Signal Transduction; WNT ligand biogenesis and trafficking; Wnt signaling pathway;

Citations


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References


Kabiri, Z; Greicius, G; et al. Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts. DEVELOPMENT 141:2206-2215(2014).
Rios-Esteves, J; Haugen, B; et al. Identification of Key Residues and Regions Important for Porcupine-mediated Wnt Acylation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:17009-17019(2014).

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