Anti-PORCN polyclonal antibody (DPABH-21827)

Rabbit anti-Human PORCN (aa 38-87) polyclonal antibody for WB, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to a region within N terminal amino acids 38-87 (ACRLLWRLGL PSYLKHASTV AGGFFSLYHF FQLHMVWVVL LSLLCYLVLF) of Human PORCN (NP_035050)
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 μg/ml; IHC-FoFr 1/300; ICC/IF: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PORCN; porcupine homolog (Drosophila); PPN; DHOF; FODH; MG61
Entrez Gene ID
UniProt ID

Product Background


Pathway
Signal Transduction; WNT ligand biogenesis and trafficking; Wnt signaling pathway;

Citations


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References


Emrick, LT; Murphy, L; et al. Prenatal Diagnosis of CLOVES Syndrome Confirmed by Detection of a Mosaic PIK3CA Mutation in Cultured Amniocytes. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2633-2637(2014).
Ross, J; Busch, J; et al. A Rare Human Syndrome Provides Genetic Evidence that WNT Signaling Is Required for Reprogramming of Fibroblasts to Induced Pluripotent Stem Cells. CELL REPORTS 9:1770-1780(2014).

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