Specifications
Immunogen
A synthetic peptide of human POLE3 is used for rabbit immunization.
Target
Alternative Names
POLE3; polymerase (DNA directed), epsilon 3 (p17 subunit); DNA polymerase epsilon subunit 3; arsenic transactivated protein; CHARAC17; CHRAC17; chromatin accessibility complex 17; DNA polymerase epsilon p17 subunit; histone fold protein CHRAC17; p17; Ybl1
Product Background
Antigen Description
POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Pathway
Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; DNA polymerase epsilon complex, organism-specific biosystem; DNA replication, organism-specific biosystem; DNA replication, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Citations
Publication ()
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