Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human DNA Polymerase beta aa 300 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P06746
Applications
Application Notes
ICC/IF: 1/50 - 1/100; IP: 1/10 - 1/100; IHC-P: 1/50 - 1/100; WB: 1/1000 - 1/10000.
Target
Alternative Names
POLB; polymerase (DNA directed), beta; DNA polymerase beta; DNA pol beta; DNA polymerase beta subunit; MGC125976;
Product Background
Antigen Description
Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Pathway
BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-6100 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
