Anti-PMM1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Mouse; Rat; Human

Immunogen

A synthetic peptide of human PMM1 is used for rabbit immunization.

Conjugate

Alternative Names

PMM1; phosphomannomutase 1; brain glucose 1; 6 bisphosphatase; Sec53; PMM 1; PMMH-22; brain glucose-1,6-bisphosphatase;

Entrez Gene ID

UniProt ID

Antigen Description

Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins.

Pathway

Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; GDP-mannose biosynthesis, organi.