The urokinase-type plasminogen activator (uPA) is one of two activators that converts plasminogen to plasmin. uPA binds with high-affinity to the cell surface via the GPI-linked receptor uPAR, which serves to localize uPA proteolytic activity. Human uPAR cDNA encodes a 335 amino acid (aa) precursor protein with a 22 aa signal peptide, five potential N-linked glycosylation sites and a C-terminal GPI-anchor site.
Pathway
Arf6 downstream pathway; Attachment of GPI anchor to uPAR; Complement and Coagulation Cascades; Complement and coagulation cascades; Dissolution of Fibrin Clot; FGF signaling pathway; Hemostasis; Metabolism of proteins;
Citations
Publication ()
Have you cited DCABY-3962 in a publication? Let us know and earn a reward for your research.
My Review for Anti-PLAUR monoclonal antibody, clone 73033
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
