Mouse myeloma cell line NS0-derived recombinant human uPAR . Leu23-Arg303 Accession Number Q03405
Conjugate
Biotin
Applications
Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-3962 - DPABY-557
The urokinase-type plasminogen activator (uPA) is one of two activators that converts plasminogen to plasmin. uPA binds with high-affinity to the cell surface via the GPI-linked receptor uPAR, which serves to localize uPA proteolytic activity. Human uPAR cDNA encodes a 335 amino acid (aa) precursor protein with a 22 aa signal peptide, five potential N-linked glycosylation sites and a C-terminal GPI-anchor site.
Pathway
Arf6 downstream pathway; Attachment of GPI anchor to uPAR; Complement and Coagulation Cascades; Complement and coagulation cascades; Dissolution of Fibrin Clot; FGF signaling pathway; Hemostasis; Metabolism of proteins;
Citations
Publication ()
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