Anti-PIP4K2A monoclonal antibody (DCABH-1760) Knockout Validated

Mouse anti-Human PIP4K2A monoclonal antibody for sELISA, WB, IHC-P

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4B4
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 304-366 of Human PIP5K2 alpha with a 26kDa propietary tag (NP_005019).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/1000; IHC-P: 5 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PIP4K2A; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha; phosphatidylinositol 4 phosphate 5 kinase, type II, alpha , PIP5K2A; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha; PIP5KIIA; PIP5KIIalpha
Entrez Gene ID
UniProt ID

Product Background


Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol-5-phosphate metabolism, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Phosphatidylinositol signaling system, organism-specific biosystem;

Citations


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References


Clarke, JH; Emson, PC; et al. Localization of phosphatidylinositol phosphate kinase II gamma in kidney to a membrane trafficking compartment within specialized cells of the nephron. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 295:F1422-F1430(2008).
Rozenvayn, N; Flaumenhaft, R; et al. Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion - Evidence for type II phosphatidylinositol 5-phosphate 4-kinase function. JOURNAL OF BIOLOGICAL CHEMISTRY 276:22410-22419(2001).

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