Anti-PIK3C2G (aa 2-100) polyclonal antibody

Species Reactivity

Human

Immunogen

PIK3C2G (NP_004561, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is AYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDEN TFFVPTAPKWDSTGHSLNEAHQISLNEFTSKSRELSWHQ

Conjugate

Alternative Names

PIK3C2G; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma; PI3K-C2GAMMA; PI3K-C2-gamma; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma; phos

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants.

Pathway

3-phosphoinositide biosynthesis; Insulin Signaling; Metabolism of lipids and lipoproteins; Phosphatidylinositol signaling system