Anti-PIGV monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PIGV is used for rabbit immunization.

Conjugate

Alternative Names

PIGV; phosphatidylinositol glycan anchor biosynthesis, class V; PIG-V; HPMRS1; GPI-MT-II; GPI mannosyltransferase 2; Ybr004c homolog; GPI mannosyltransferase II; dol-P-Man dependent GPI mannosyltransferase;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene.

Pathway

GPI-anchor biosynthesis, core oligosaccharide; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolism of proteins; Post-translational modification: synthesis of GPI-anchored proteins; Post-translational protein modification; Synthesis of glycosylphosphatidylinositol (GPI);