Anti-PIGV polyclonal antibody (DPABH-22149)

Rabbit anti-Human PIGV (aa 51-100) polyclonal antibody for IHC-P, WB Datasheet

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Host Species
Antibody Isotype
Species Reactivity
Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (FVDQLVEGLL GGLSHWDAEH FLFIAEHGYL YEHNFAFFPG FPLALLVGTE) of Human PIGV (NP_060307)


Application Notes
IHC-P: 4 - 8 μg/ml; WB: 5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.


Alternative Names
PIGV; phosphatidylinositol glycan anchor biosynthesis, class V; PIG-V; HPMRS1; GPI-MT-II; GPI mannosyltransferase 2
Entrez Gene ID
UniProt ID

Product Background

GPI-anchor biosynthesis, core oligosaccharide; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis; Metabolism of proteins; Post-translational protein modification


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Hirata, T; Fujita, M; et al. Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability. JOURNAL OF BIOCHEMISTRY 154:257-264(2013).
Murakami, Y; Krawitz, PM; et al. Release of Alkaline Phosphatase Caused by PIGV Mutations In Patients with Hyperphosphatasia-Mental Retardation Syndrome (HPMR), a Recently Found Second Inherited GPI Anchor Deficiency. BLOOD 116:844-844(2010).

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