Anti-PIGK (aa 268-366) polyclonal antibody

Species Reactivity

Human

Immunogen

PIGK (NP_005473, 268 a.a. ~ 366 a.a) partial recombinant protein with GST tag. The sequence is MNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIME SSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPKLKDWHP

Conjugate

Alternative Names

PIGK; phosphatidylinositol glycan anchor biosynthesis, class K; GPI8; GPI-anchor transamidase; PIG-K; GPI8 homolog; GPI transamidase subunit; phosphatidylinositol glycan, class K; phosphatidylinositol-glycan biosynthesis class K protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

Pathway

Attachment of GPI anchor to uPAR; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis; Post-translational modification: synthesis of GPI-anchored proteins;