Anti-PIGK monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Mouse; Rat; Human

Immunogen

A synthetic peptide of human PIGK is used for rabbit immunization.

Conjugate

Alternative Names

PIGK; phosphatidylinositol glycan anchor biosynthesis, class K; phosphatidylinositol glycan, class K; GPI-anchor transamidase; GPI transamidase subunit; GPI8; hGPI8; PIG-K; GPI8 homolog; phosphatidylinositol-glycan biosynthesis class K protein; MGC22559;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

Pathway

Attachment of GPI anchor to uPAR, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Post-translational modification: synthesis of GPI-anchored proteins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem;