Synthetic peptide within Human Pellino 2 aa 22-51 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9HAT8
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500;
Target
Alternative Names
PELI2; pellino E3 ubiquitin protein ligase family member 2; E3 ubiquitin-protein ligase pellino homolog 2; pellino-2; pellino homolog 2; protein pellino homolog 2;
Scaffold protein which probably links Toll like receptors (TLRs) to basic cellular processes via its interaction with the complex containing IRAK (IL1R associated kinase) kinases and TRAF6. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation.
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