General Notes
This product (Catalog No. DPABH-23054) is a rabbit-derived polyclonal antibody raised against human PELI2, targeting the amino acid region 281–420 of the protein. This antibody exhibits cross-reactivity with Human PELI2 from mouse and rat. It has been affinity purified by Protein A. Pellino2 (PELI2) is a newly discovered E3 ubiquitin ligase, which regulates the protein degradation, protein-protein interaction, protein translocation and signaling transduction via the ubiquitination of target proteins, and plays important roles in inflammation and the immune system. PELI2 possesses a C-terminal RING-like domain and a phospho-threonine-binding forkhead-associated (FHA) domain that are responsible for ubiquitin ligase activity and substrate binding, respectively (PMID: 24699078).IHC.
DPABH-23054 is suitable for use in Western blot (WB) (1:500–1:3,000), IF/ICC (1:50–1:500) applications.
DPABH-23054 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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