Specifications
Species Reactivity
Mouse; Rat; Cow; Human; C. elegans; Fruit fly
Immunogen
Human Pyruvate Dehydrogenase E1-alpha subunit.
Applications
Application Notes
WB: 0.5 - 1 μg/ml; ICC/IF: 1 μg/ml; Flow Cyt: 1 μg/ml;
Target
Alternative Names
PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1; PDHA; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; PDHE1-A type I; pyruvate dehydrogenase complex, E1-alpha polypeptide 1; PHE1A; PDHCE1A;
Product Background
Antigen Description
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Pathway
Acetylcholine Synthesis, organism-specific biosystem; Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem;
Citations
Publication ()
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COA
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