Magic™ Anti-PDGFRB (Phospho Y1021) monoclonal antibody, clone FQS3587

Name: Magic™ Anti-PDGFRB (Phospho Y1021) monoclonal antibody, clone FQS3587
SKU: DCABH-2906
Rating: 5 (1 reviews)

Rabbit Anti-Human PDGFRB (Phospho Y1021) monoclonal antibody for WB, IP, FC

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS3587

Species Reactivity

Mouse

Immunogen

A phospho specific peptide corresponding to residues surrounding tyrosine 1021 of Human PDGF Receptor beta

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/50000 - 1/200000; IP: 1/10 - 1/100; Flow Cyt: 1/10 - 1/100

Target

Alternative Names

PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-typ

Entrez Gene ID

5159

UniProt ID

P09619

Product Background

Antigen Description

Receptor that binds specifically to PDGFB and PDGFD and has a tyrosine-protein kinase activity. Phosphorylates Tyr residues at the C-terminus of PTPN11 creating a binding site for the SH2 domain of GRB2.

Pathway

Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signal transduction, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;

Citations