Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PDE10A aa 650-750 (Cysteine residue). The exact sequence is proprietary.Database link: Q9Y233
Applications
Application Notes
WB: 1/1000 - 1/5000; IP: 1/10 - 1/100; Flow Cyt: 1/100 - 1/500;
Target
Alternative Names
PDE10A; phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase 10A; phosphodiesterase 10A1 (PDE10A1); dJ416F21.1 (phosphodiesterase 10A); HSPDE10A; FLJ11894; FLJ25677;
Product Background
Antigen Description
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Pathway
G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Hemostasis, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem;
Citations
Publication ()
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COA
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