RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
Pathway
Deadenylation-dependent mRNA decay; Decapping complex; RNA degradation; mRNA decay by 5 to 3 exoribonuclease.
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