Synthetic peptide within Human PATL1 aa 550-600. The exact sequence is proprietary. NP_689929.2Sequence: E RPALMDDRKH KICSMYDNLR GKLPGQERPS DDHFVQIMCI RKGKRMVARI Database link: Q86TB9
Conjugate
Unconjugated
Applications
Application Notes
IP: 2-10 μg/mg
Target
Alternative Names
PATL1; protein associated with topoisomerase II homolog 1 (yeast); Pat1b; hPat1b; protein PAT1 homolog 1; PAT1-like protein 1; protein PAT1 homolog b;
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
Pathway
Deadenylation-dependent mRNA decay; Decapping complex; RNA degradation; mRNA decay by 5 to 3 exoribonuclease
Citations
Publication ()
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