A synthetic peptide of human PAK1IP1 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
PAK1IP1; PAK1 interacting protein 1; p21-activated protein kinase-interacting protein 1; bA421M1.5; FLJ20624; hPIP1; MAK11; PIP1; WDR84; PAK1-interacting protein 1; PAK/PLC-interacting protein 1; WD repeat-containing protein 84; RP11-421M1.5;
PAK1 interacting protein 1 (PAK1IP1) negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N terminal regulatory domain. PAK1IP1 also binds to the N terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.
Citations
Publication ()
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