Rabbit Anti-Human PAICS (N-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Fusion protein corresponding to residues near the N terminal of human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

Conjugate

Application Notes

WB: 1:1000-1:5000
IHC: 1:50-1:200

General Notes

This product (Catalog No. DPABH-03507) is a rabbit-derived IgG polyclonal antibody raised against human PAICS. It has been affinity purified by protein A. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
DPABH-03507 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:50–1:200) applications.
DPABH-03507 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ADE2; AIRC; PAIS; ADE2H1

Entrez Gene ID

UniProt ID