Anti-PAICS monoclonal antibody (DCABH-572)

Mouse anti-Human PAICS monoclonal antibody for WB, ICC/IF, FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
6C7
Species Reactivity
Human
Immunogen
Recombinant full length Human PAICS produced in HEK293T cells (NP_006443).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; ICC/IF: 1/100; Flow Cyt: 1/10000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PAICS; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; PAIS; multifunctional protein ADE2; ADE2H1; AIRC
Entrez Gene ID
UniProt ID

Product Background


Pathway
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, organism-specific biosystem; Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem;

Citations


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References


Ginder, ND; Binkowski, DJ; et al. Nucleotide complexes of Escherichia coli phosphoribosylaminoimidazole succinocarboxamide synthetase. JOURNAL OF BIOLOGICAL CHEMISTRY 281:20680-20688(2006).
Li, SX; Tong, YP; et al. Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis. JOURNAL OF MOLECULAR BIOLOGY 366:1603-1614(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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