DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3 to the lesion.
Pathway
Base Excision Repair; Base excision repair; Base-Excision Repair, AP Site Formation; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway; Cleavage of the damaged purine; DNA Repair;
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