Synthetic Mouse OGG1 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-Ogg1 (mouse) antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; DNA N-glycosylase activity; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; catalytic activity; damaged DNA binding; hydrolase activity; hydrolase activity, acting on gly
OGG1; 8-oxoguanine DNA-glycosylase 1; N-glycosylase/DNA lyase; Mmh;