Full length protein corresponding to Human Nuf2 aa 1-464.Sequence: METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYM RALQIVYGIRLEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICR VNDFETADILCPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSAD KMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSD
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Pathway
Cell Cycle; Cell Cycle, Mitotic; DNA Replication; M Phase; Mitotic M-M/G1 phases; Mitotic Prometaphase;
Citations
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