Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Nuf2 aa 1-100 (Cysteine residue). The exact sequence is proprietary.Database link: Q9BZD4
Applications
Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/10 - 1/100; ICC/IF: 1/500.
Target
Alternative Names
NUF2; NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae); CDCA1, cell division cycle associated 1; kinetochore protein Nuf2; cancer/testis antigen 106; CT106; NUF2R; hNuf2; hNuf2R; hsNuf2; cell division cycle associated 1; cell division c
Product Background
Antigen Description
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem; Mitotic Prometaphase, organism-specific biosystem;
Citations
Publication ()
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