Anti-NRG1 polyclonal antibody [Biotin] (DPABY-396)

Goat Anti-Human NRG1 polyclonal antibody for WB, ELISA(Det)

Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
E. coli-derived recombinant human NRG1-beta 1/HRG1-beta 1 . Ser2-Lys246 Accession Number AAA58639
Conjugate
Biotin

Applications


Application Notes
Western Blot: 0.1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-3958 - DPABY-396
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
NRG1; neuregulin 1; GGF; HGL; HRG; NDF
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Cardiac Progenitor Differentiation; Constitutive PI3K/AKT Signaling in Cancer; DAP12 interactions; DAP12 signaling; Disease; Downregulation of ERBB2:ERBB3 signaling; Downstream signal transduction;

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References


Edwards, JM; Bottenstein, JE; et al. Neuregulin 1 growth factors regulate proliferation but not apoptosis of a CNS neuronal progenitor cell line. BRAIN RESEARCH 1108:63-75(2006).
Raj, EH; Skinner, A; et al. Neuregulin 1-alpha expression in locally advanced breast cancer. BREAST 10:41-45(2001).

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