Anti-NRG1 monoclonal antibody (DCABY-3958)

Mouse Anti-Human NRG1 monoclonal antibody for WB, ELISA(Cap) Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
258806
Species Reactivity
Human
Immunogen
E. coli-derived recombinant human NRG1-beta 1/HRG1-beta 1. Ser2-Lys246 Accession Number AAA58639
Conjugate
Unconjugated

Applications


Application Notes
Western Blot: 2 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-3958 - DPABY-396
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
NRG1; neuregulin 1; GGF; HGL; HRG; NDF
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Cardiac Progenitor Differentiation; Constitutive PI3K/AKT Signaling in Cancer; DAP12 interactions; DAP12 signaling; Disease; Downregulation of ERBB2:ERBB3 signaling; Downstream signal transduction;

Citations


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References


Garner, AP; Bialucha, CU; et al. An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin. CANCER RESEARCH 73:6024-6035(2013).
Dunn, M; Sinha, P; et al. Co-expression of neuregulins 1, 2, 3 and 4 in human breast cancer. JOURNAL OF PATHOLOGY 203:672-680(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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