NPY5R (neuropeptide Y receptor Y5) is a protein-coding gene. Diseases associated with NPY5R include papillon-lefevre disease, and cocaine dependence, and among its related super-pathways are Class A/1 (Rhodopsin-like receptors) and Peptide GPCRs. GO annotations related to this gene include neuropeptide Y receptor activity and pancreatic polypeptide receptor activity. An important paralog of this gene is GPR83. Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
Pathway
Class A/1 (Rhodopsin-like receptors); G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Neuroactive ligand-receptor interaction; Peptide GPCRs; Peptide ligand-binding receptors; Signal Transduction; Signaling by GPCR;
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