NOTCH1 (notch 1) is a protein-coding gene. Diseases associated with NOTCH1 include left ventricular outflow tract obstruction, and nerve compression syndrome, and among its related super-pathways are Constitutive Signaling by NOTCH1 PEST Domain Mutants and Notch signaling pathway. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is EYS.
Pathway
Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant; Developmental Biology
Citations
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