Anti-NOL6 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human NOL6 is used for rabbit immunization.

Conjugate

Alternative Names

NOL6; nucleolar protein 6 (RNA-associated); NRAP; UTP22; bA311H10.1; nucleolar protein 6; nucleolar RNA-associated protein; nucleolar protein family 6 (RNA-associated);

Entrez Gene ID

UniProt ID

Antigen Description

The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.

Pathway

Ribosome biogenesis in eukaryotes;