Anti-NMNAT3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human NMNAT3 is used for rabbit immunization.

Conjugate

Alternative Names

NMNAT3; nicotinamide nucleotide adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; PNAT3; NMN adenylyltransferase 3; NaMN adenylyltransferase 3; pyridine nucleotide adenylyltransferase 3; nicotinate-nucleotide adenylyltransferase 3;

Entrez Gene ID

UniProt ID

Antigen Description

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).

Pathway

Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; NAD biosynthesis II (from tryptophan), organism-specific biosystem; NAD biosynthesis III, organism-specific biosystem; NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde, organism-specific biosystem;