A synthetic peptide of human NDFIP2 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
NDFIP2; Nedd4 family interacting protein 2; NEDD4 family-interacting protein 2; KIAA1165; N4wbp5a; NF-kappa-B-activating protein 413; NEDD4 WW domain-binding protein 5A; putative NF-kappa-B-activating protein 413; MAPK-activating protein PM04 PM05 PM06 PM
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.
Citations
Publication ()
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