General Notes
This product (Catalog No. DPABH-24787) is a rabbit-derived polyclonal antibody raised against human NCAM2, targeting the amino acid region 21–297 of the protein. This antibody exhibits cross-reactivity with Human NCAM2 from mouse and rat. It has been affinity purified by Protein A. The mammalian NCAM family has two members, NCAM1 and NCAM2. Neural cell adhesion molecule 2 (NCAM2, also known as NCAM21) is a single-pass type I membrane protein that is highly expressed in the brain, which may play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons or in neurodegenerative diseases such as Alzheimer's disease (PMID: 26611261). NCAM2 has two isoforms: NCAM2.1 bearing transmembrane and cytoplasmic domains and the shorter NCAM2.2 isoform, which is GPI-anchored. The molecular weight of NCAM2 is around 125 kDa and 93 kDa.
DPABH-24787 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-24787 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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