Specifications
Immunogen
A synthetic peptide of human NAPRT1 is used for rabbit immunization.
Target
Alternative Names
NAPRT1; nicotinate phosphoribosyltransferase domain containing 1; nicotinate phosphoribosyltransferase; PP3856; NAPRTase; FHA-HIT-interacting protein; nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain-containing protein
Product Background
Antigen Description
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
Pathway
Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Nicotinamide salvaging, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem;
Citations
Publication ()
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