Rabbit Anti-Human MAEL (a.a. 282-434) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human MAEL protein; Source: E. coli derived, PET30a; Tag: 6*His; Domain: 282-434 aa of BC028595

Conjugate

Application Notes

WB: 1:1000-1:4000
IHC: 1:50-1:500

General Notes

This product (Catalog No. CPBT-39551RM) is a rabbit-derived polyclonal antibody raised against human MAEL, targeting the amino acid region 282–434 of the protein. This antibody exhibits cross-reactivity with Human MAEL from mouse and rat. It has been affinity purified by Protein A. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage.
CPBT-39551RM is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:50–1:500) applications.
CPBT-39551RM is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

MAEL; maelstrom homolog (Drosophila); Protein maelstrom homolog; RP11 102C16.1

Entrez Gene ID

UniProt ID