Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
A phospho specific peptide corresponding to amino acids residues Threonine 17 and Serine 18 of Human MRLC3 (P19105).
Applications
Application Notes
WB: 1/1000 - 1/10000.
Target
Alternative Names
MYL12A; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light polypeptide, regulatory, non sarcomeric (20kD); myosin regulatory light chain 12A; MLCB; MRCL3; MRLC3; MYL2B; myosin regulatory light chain 3; MLC-2B; myosin RLC; myosin regulatory
Product Background
Antigen Description
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
Pathway
Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem; Tight junction, organism-specific biosystem;
Citations
Publication ()
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COA
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