Specifications
Immunogen
Synthetic peptide: EQKLISEEDL, corresponding to amino acids 410-419 of Human c-Myc.
Applications
Application Notes
ICC/IF: 1/500 - 1/5000.
Target
Alternative Names
MYC; v-myc myelocytomatosis viral oncogene homolog (avian); v myc avian myelocytomatosis viral oncogene homolog; myc proto-oncogene protein; bHLHe39; c Myc; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian m
Product Background
Antigen Description
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5-CAC[GA]TG-3. Seems to activate the transcription of growth-related genes.
Pathway
Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Apoptosis, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; C-MYC pathway, organism-specific biosystem;
Citations
Publication ()
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