Specifications
Immunogen
A synthetic peptide of human MTTP is used for rabbit immunization.
Target
Alternative Names
MTTP; microsomal triglyceride transfer protein; microsomal triglyceride transfer protein (large polypeptide, 88kD) , microsomal triglyceride transfer protein (large polypeptide, 88kDa) , MTP; microsomal triglyceride transfer protein large subunit; ABL; mi
Product Background
Antigen Description
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
Pathway
Chylomicron-mediated lipid transport, organism-specific biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem.
Citations
Publication ()
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