Anti-MTHFD2 (aa 278-307) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide within Human MTHFD2 aa 278-307 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: P13995

Conjugate

Application Notes

Flow Cyt: 1/10 - 1/50; IHC-P: 1/10 - 1/50; WB: 1/1000.

Alternative Names

MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; NAD-dependent methylene tetrahydrofolate dehydrogenase cycloh

Entrez Gene ID

UniProt ID

Antigen Description

MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with MTHFD2 include follicular lymphoma, and spina bifida, and among its related super-pathways are One carbon pool by folate and Histidine catabolism. GO annotations related to this gene include phosphate ion binding and nucleotide binding. An important paralog of this gene is MTHFD2L.

Pathway

C1-unit interconversion, eukaryotes; Metabolic pathways; Nucleotide Metabolism; One Carbon Metabolism; One carbon pool by folate;