Anti-MTHFD2 (aa 30-304) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant fragment, corresponding to a region within amino acids 30-304 of Human MTHFD2 (UniProt ID: P13995).

Conjugate

Application Notes

WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000; ICC/IF: 1/100 - 1/1000.

Alternative Names

MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; NAD-dependent methylene tetrahydrofolate dehydrogenase cycloh

Entrez Gene ID

UniProt ID

Antigen Description

MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with MTHFD2 include follicular lymphoma, and spina bifida, and among its related super-pathways are One carbon pool by folate and Histidine catabolism. GO annotations related to this gene include phosphate ion binding and nucleotide binding. An important paralog of this gene is MTHFD2L.

Pathway

C1-unit interconversion, eukaryotes; Metabolic pathways; Nucleotide Metabolism; One Carbon Metabolism; One carbon pool by folate;