General Notes
This product (Catalog No. DPABH-11099) is a rabbit-derived polyclonal antibody raised against human MTHFD1, targeting the amino acid region 1–297 of the protein. It has been affinity purified by Protein A. MTHFD1 (Methylenetetrahydrofolate Dehydrogenase 1) is a critical trifunctional enzyme located in the cytoplasm and nucleus that plays a central role in one-carbon metabolism. It catalyzes three sequential reactions involving folate derivatives, essential for purine, thymidylate, and methionine biosynthesis, thereby supporting DNA synthesis, repair, and methylation.
DPABH-11099 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-11099 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.