Specifications
Immunogen
Full length Human recombinant EI2BL protein produced in HEK293T cells (NP_115661).
Applications
Application Notes
WB: 1/2000; IHC-P: 1/50; ICC/IF: 1/50 - 1/100;
Target
Alternative Names
MRI1; methylthioribose-1-phosphate isomerase homolog (S. cerevisiae); methylthioribose-1-phosphate isomerase; MGC3207; MTNA; Ypr118w; M1Pi; MTR-1-P isomerase; mediator of RhoA-dependent invasion; S-methyl-5-thioribose-1-phosphate isomerase; translation in
Product Background
Antigen Description
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Pathway
Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Metabolism of polyamines, organism-specific biosystem; Methionine salvage pathway, organism-specific biosystem;
Citations
Publication ()
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COA
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