Anti-MRI1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human MGC3207 is used for rabbit immunization.

Conjugate

Alternative Names

MRI1; methylthioribose-1-phosphate isomerase 1; MRDI; MTNA; Ypr118w; methylthioribose-1-phosphate isomerase; M1Pi; MTR-1-P isomerase; mediator of RhoA-dependent invasion; S-methyl-5-thioribose-1-phosphate isomerase 1; methylthioribose-1-phosphate isomeras

Entrez Gene ID

UniProt ID

Antigen Description

MRI1 (methylthioribose-1-phosphate isomerase 1) is a protein-coding gene. Diseases associated with MRI1 include spinal cord melanoma, and visual agnosia, and among its related super-pathways are S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I and Metabolic pathways. GO annotations related to this gene include S-methyl-5-thioribose-1-phosphate isomerase activity and identical protein binding. Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Pathway

Cysteine and methionine metabolism;Metabolism; Metabolism of amino acids and derivatives; Metabolism of polyamines; Methionine salvage pathway; Methionine salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I; Sulfur amino acid metabolism;