Anti-MICB (full length) polyclonal antibody

Name: Anti-MICB (full length) polyclonal antibody
SKU: DPABH-06626
Rating: 5 (1 reviews)

Mouse anti-Human MICB (full length) polyclonal antibody for WB

COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Full length protein corresponding to amino acids 1-340 of Human MICB (AAH44218.1).

Conjugate

Unconjugated

Applications

Application Notes

WB: 1 μg/ml.

Target

Alternative Names

MICB; MHC class I polypeptide-related sequence B; PERB11.2; MIC-B; MHC class I mic-B antigen; stress inducible class I homolog; MHC class I chain-related protein B; MHC class I-like molecule PERB11.2-IMX;

Entrez Gene ID

4277

UniProt ID

B4DUT9

Product Background

Antigen Description

Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Pathway

Adaptive Immune System; Immune System; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Natural killer cell mediated cytotoxicity;

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Activation of Liver X Receptor upregulates the expression of the NKG2D ligands MICA and MICB in Multiple Myeloma through different molecular mechanisms

EUROPEAN JOURNAL OF IMMUNOLOGY

Authors: Bilotta, M. T.; Abruzzese, M. P.; Molfetta, R.; Scarno, G.; Fionda, C.; Zingoni, A.; Soriani, A.; Garofalo, T.; Petrucci, M. T.; Ricciardi, M. R.; Paolini, R.; Santoni, A.; Cippitelli, M.

Abstract

Interaction of the HCMV glycoprotein UL16 with the NKG2D ligand MICB

IMMUNOBIOLOGY

Authors: [Anonymous]

Abstract