Anti-MICA polyclonal antibody [Biotin] (DPABY-581)

Goat Anti-Human MICA polyclonal antibody for WB, IHC, ELISA(Det) Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Mouse myeloma cell line NS0-derived recombinant human MICA. Ala22-Gln308 Accession Number NP_001170990
Conjugate
Biotin

Applications


Application Notes
Western Blot: 0.1 μg/mL; Immunohistochemistry: 5-15 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4106 - DPABY-581
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
MICA; MHC class I polypeptide-related sequence A; MIC-A; PERB11.1; HLA class I antigen; stress inducible class I homolog
Entrez Gene ID
UniProt ID

Product Background


Pathway
Allograft Rejection; Natural killer cell mediated cytotoxicity;

Citations


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References


Andre, P; Castriconi, R; et al. Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors. EUROPEAN JOURNAL OF IMMUNOLOGY 34:961-971(2004).
Narayan, S; Tsai, EW; et al. Acute rejection associated with donor-specific anti-MICA antibody in a highly sensitized pediatric renal transplant recipient. PEDIATRIC TRANSPLANTATION 15:E1-E7(2011).

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