Anti-MGAT4B (aa 401-500) polyclonal antibody

Species Reactivity

Human

Immunogen

MGAT4B (NP_055090, 401 a.a. ~ 500 a.a) partial recombinant protein with GST tag. The sequence is AEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERFFFRSGNIEHPE DKLFNTSVEVLPFDNPQSDKEALQEGRTATLRYPRSPDGY

Conjugate

Alternative Names

MGAT4B; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B; GNT-IV; GNT-IVB; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B; glcNAc-T IVb; aminyltransferase; N-acetylglucosaminyltransferase IVb

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.

Pathway

Asparagine N-linked glycosylation; N-Glycan antennae elongation; N-Glycan biosynthesis; N-glycan biosynthesis, complex type