Anti-MGAT4B (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant full length protein, corresponding to amino acids 1-563 of Human MGAT4B, Isoform 3 (Gene ID: 11282, UniProt ID: Q9UQ53-3).

Conjugate

Alternative Names

MGAT4B; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B; mannosyl (alpha 1,3 ) glycoprotein beta 1,4 N acetylglucosaminyltransferase, isoenzyme B; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferas

Entrez Gene ID

UniProt ID

Antigen Description

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.

Pathway

Asparagine N-linked glycosylation; Metabolic pathways; Metabolism of proteins; N-Glycan antennae elongation; N-Glycan biosynthesis; N-glycan antennae elongation in the medial/trans-Golgi;